{"product_id":"cyp11a1-polyclonal-antibody-e-ab-67057","title":"CYP11A1 Polyclonal Antibody - E-AB-67057","description":"\u003cp\u003eCYP11A1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-67057-60, E-AB-67057-120, E-AB-67057-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CYP11A1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CYP11A1; CYP11A; CYPXIA1; P450SCC\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P05108\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human CYP11A1 (NP_000772.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IHC \t1:20-1:50   IF \t1:20-1:50\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 42kDa\/60kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 50kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146435985587,"sku":"E-AB-67057-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146436018355,"sku":"E-AB-67057-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146436051123,"sku":"E-AB-67057-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_6e00fbbb-917f-4ad1-8ee9-7d75c602832c.png?v=1710295520","url":"https:\/\/afsbio.com\/products\/cyp11a1-polyclonal-antibody-e-ab-67057","provider":"AFSBio Inc.","version":"1.0","type":"link"}