{"product_id":"cyp1a1-monoclonal-antibody-bt-mca4492","title":"CYP1A1 Monoclonal Antibody - BT-MCA4492","description":"\u003cp\u003eCYP1A1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4492-50, BT-MCA4492-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CYP1A1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 6G5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CYP1A1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CYP1A1 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 58kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P04798\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1543\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238583460019,"sku":"BT-MCA4492-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238583492787,"sku":"BT-MCA4492-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a13a94fc-e5d5-44ff-9ebf-344a945fe744.png?v=1769382804","url":"https:\/\/afsbio.com\/products\/cyp1a1-monoclonal-antibody-bt-mca4492","provider":"AFSBio Inc.","version":"1.0","type":"link"}