{"product_id":"cystatin-c-7f11-mouse-mab-em1275","title":"Cystatin C (7F11) Mouse mAb - EM1275","description":"\u003cp\u003eCystatin C (7F11) Mouse mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EM1275-50, EM1275-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: AD8, Cystatin3, Gamma trace, HCCAA\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB  1:1, 000-2, 000 IHC 1:100-200  ELISA  1:10, 000-20, 000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant Protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 14kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 1471\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P01034\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Secreted\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201993728179,"sku":"EM1275-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201993760947,"sku":"EM1275-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_39124d64-19ca-4259-b2ef-bd8cf0681834.png?v=1767119535","url":"https:\/\/afsbio.com\/products\/cystatin-c-7f11-mouse-mab-em1275","provider":"AFSBio Inc.","version":"1.0","type":"link"}