{"product_id":"cytokeratin-10-y160-polyclonal-antibody-bs1199","title":"Cytokeratin 10 (Y160) Polyclonal Antibody-BS1199","description":"\u003cp\u003eCytokeratin 10 (Y160) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1199-50, BS1199-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P13645\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IHC: 1:50~1:200 \u003cbr\u003e\nIF: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 10 is a heterotetramer of two type I and two type II keratins, is generally associated with keratin 1, and is seen in all suprabasal cell layers including stratum corneum.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemistry (IHC) analyzes of Cytokeratin 10 (Y160) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 59 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Cytokeratin 10 (Y160) polyclonal antibody detects endogenous levels of Cytokeratin 10 protein.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Keratin, type I cytoskeletal 10; Cytokeratin-10; Short name=CK-10; Keratin-10; Short name=K10; KRT10; KPP; CK-10; CK 10; CK10; Keratin 10; Keratin10\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 130-180 of Human Cytokeratin 10.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939256111283,"sku":"BS1199-50","price":254.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939256144051,"sku":"BS1199-100","price":442.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_87239f27-93a0-40c5-820a-a8719b20ef32.jpg?v=1704545563","url":"https:\/\/afsbio.com\/products\/cytokeratin-10-y160-polyclonal-antibody-bs1199","provider":"AFSBio Inc.","version":"1.0","type":"link"}