{"product_id":"cytokeratin-19-krt19-rabbit-polymab®-a0247pm","title":"Cytokeratin 19 (KRT19) Rabbit PolymAb® - A0247PM","description":"\u003cp\u003eCytokeratin 19 (KRT19) Rabbit PolymAb®\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A0247PM-20, A0247PM-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 44kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 44kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3880\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P08727\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: K19; CK19; K1CS\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:1000 - 1:10000 IF\/ICC, 1:200 - 1:800 IHC-P, 1:4000 - 1:20000 ELISA, Recommended starting concentration is 1 µg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Intermediate Filaments, Extracellular Matrix, Keratin, Stem Cells.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: KRT19\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189436342451,"sku":"A0247PM-20","price":165.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189436375219,"sku":"A0247PM-100","price":431.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_0658ecf6-56b4-4753-abc5-f8b0ffbf270e.png?v=1766427187","url":"https:\/\/afsbio.com\/products\/cytokeratin-19-krt19-rabbit-polymab%c2%ae-a0247pm","provider":"AFSBio Inc.","version":"1.0","type":"link"}