{"product_id":"cytokeratin-8-krt8-rabbit-pab-a1024","title":"Cytokeratin 8 (KRT8) Rabbit pAb - A1024","description":"\u003cp\u003eCytokeratin 8 (KRT8) Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A1024-20, A1024-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, IF\/ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 54 kDa\/56 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 54 kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3856\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P05787\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: K8; KO; CK8; CK-8; CYK8; K2C8; CARD2; Cytokeratin 8 (KRT8)\u003c\/p\u003e \n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:2000 - 1:4000 IHC-P, 1:50 - 1:200 IF\/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Invasion and Metastasis, Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Intermediate Filaments.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: KRT8\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189465374899,"sku":"A1024-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189465407667,"sku":"A1024-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_bd06cfbb-764e-485a-b42c-5541916ac29e.png?v=1766427786","url":"https:\/\/afsbio.com\/products\/cytokeratin-8-krt8-rabbit-pab-a1024","provider":"AFSBio Inc.","version":"1.0","type":"link"}