{"product_id":"cytokeratin-9-polyclonal-antibody-bs90390","title":"Cytokeratin 9 Polyclonal Antibody-BS90390","description":"\u003cp\u003eCytokeratin 9 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90390-50, BS90390-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P35527(Human) Q6RHW0(Mouse) Q8CIS9(Rat)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IP\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500-1:1,000\u003cbr\u003e\nIHC:1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratin 9 is an unusually large, type I acidic cytokeratin that differentiates human plantar and palmar epidermal cells. Cytokeratin 9 localizes to the suprabasal layers as well as the upper epidermal layers such as the glandular ridges and interridges. The domains of cytokeratin 9 include a head, an α-helical coiled-coil-forming rod, and a tail; cytokeratin 9 shares significant homology with cytokeratin 10. Mutations in the cytokeratin 9 gene correlate with the development of epidermolytic palmoplantar keratoderma (EPPK), an autosomal dominant inherited skin disorder that is characterized by hyperkeratosis of the skin over the palms and soles.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Cytokeratin 9 antibody. Counter stained with hematoxylin.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 62 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Cytokeratin 9 polyclonal antibody detects endogenous levels of Cytokeratin 9 protein.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CK-9, K9, KRT9, CK 9, CK-9, Cytokeratin 9, Cytokeratin-9, Cytokeratin9, EPPK, K1C9, K9, Keratin 9, Keratin, Keratin type I cytoskeletal 9, Keratin-9, Keratin9, KRT 9, Krt9, Spermatid Perinuclear Ring Manchette Protein K9, type I cytoskeletal 9,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: recombinant protein\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939198865587,"sku":"BS90390-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939198898355,"sku":"BS90390-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_42b4ab81-1194-4edb-9a1b-d5c72932a607.jpg?v=1704544970","url":"https:\/\/afsbio.com\/products\/cytokeratin-9-polyclonal-antibody-bs90390","provider":"AFSBio Inc.","version":"1.0","type":"link"}