{"product_id":"cytokeratin-ae3-rabbit-pab-a26789","title":"Cytokeratin AE3 Rabbit pAb - A26789","description":"\u003cp\u003eCytokeratin AE3 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A26789-20, A26789-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 66kDa\/65kDa\/64kDa\/56kDa\/62kDa\/60kDa\/51kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 28-60kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3848\/3849\/3850\/3851\/3852\/3853\/3855\/3856\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P04264\/P35908\/P12035\/P19013\/P13647\/P02538\/P08729\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: K1; CK1; EHK; AEI2; EHK1; EPPK; KRT1A; NEPPK\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:3000 - 1:18000 IHC-P, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 µg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Tags \u0026amp; Cell Markers Subcellular Markers Cytoskeleton IntermediateSignal Transduction Cytoskeleton \/ ECM Cytoskeleton Intermediate Filaments Class I Cytokeratins\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Cytokeratin AE3\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189883855027,"sku":"A26789-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189883887795,"sku":"A26789-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_7189fced-a3ce-4fb7-9fb0-b6bd692c9e42.png?v=1766437418","url":"https:\/\/afsbio.com\/products\/cytokeratin-ae3-rabbit-pab-a26789","provider":"AFSBio Inc.","version":"1.0","type":"link"}