{"product_id":"cytokeratin-pan-acetyl-lys194-rabbit-pab-es1117","title":"Cytokeratin-pan (Acetyl Lys194) rabbit pAb - ES1117","description":"\u003cp\u003eCytokeratin-pan (Acetyl Lys194) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1117-50, ES1117-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: keratin 2 (KRT2) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: KRT2; KRT2A; KRT2E; Keratin, type II cytoskeletal 2 epidermal; Cytokeratin-2e; CK-2e; Epithelial keratin-2e; Keratin-2 epidermis; Keratin-2e; K2e; Type-II keratin Kb2; KRT76; KRT2B; KRT2P; Keratin, type II cytoskeletal 2 oral; Cytokeratin-2PCK-2P; K2P; Keratin-76; K76; Type-II keratin Kb9; KRT3; Keratin, type II cytoskeletal 3; 65 kDa cytokeratin; Cytokeratin-3; CK-3; Keratin-3; K3; Type-II keratin Kb3; KRT5; Keratin, type II cytoskeletal 5; 58 kDa cytokeratin; Cytokeratin-5; CK-5; Keratin-5\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized Acetyl-peptide derived from human Keratin-pan around the Acetylation site of Lys194. AA range:151-200\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 65kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3849\/51350\/3850\/3852\/3853\/3854\/286887\/112802\/140807\/319101\/121391\/9119\/338785\/3856\/3890\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P35908\/Q01546\/P12035\/P13647\/P02538\/P04259\/P48668\/Q3SY84\/Q14CN4\/Q86Y46\/Q7RTS7\/O95678\/Q5XKE5\/P08729\/P05787\/Q9NSB2\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: extracellular space, nucleus, cytoplasm, Golgi apparatusintermediate filament, membrane, keratin filament, intermediate filament cytoskeleton, extracellular exosome,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202002673843,"sku":"ES1117-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202002706611,"sku":"ES1117-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_1174b8e0-8e5d-4f51-a193-17a15d4fd7dd.png?v=1767119721","url":"https:\/\/afsbio.com\/products\/cytokeratin-pan-acetyl-lys194-rabbit-pab-es1117","provider":"AFSBio Inc.","version":"1.0","type":"link"}