{"product_id":"d3dr-polyclonal-antibody-bt-ap02486","title":"D3DR Polyclonal Antibody - BT-AP02486","description":"\u003cp\u003eD3DR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02486-20, BT-AP02486-50, BT-AP02486-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: DRD3 encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DRD3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: D3DR Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 44225\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P35462; Mouse: P30728; Rat: P19020\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DRD3; D(3) dopamine receptor; Dopamine D3 receptor\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1814; Mouse: 13490; Rat: 29238\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240255054003,"sku":"BT-AP02486-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240255086771,"sku":"BT-AP02486-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240255119539,"sku":"BT-AP02486-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6603df2d-cc93-445b-bde2-abceb83df4dd.png?v=1769405788","url":"https:\/\/afsbio.com\/products\/d3dr-polyclonal-antibody-bt-ap02486","provider":"AFSBio Inc.","version":"1.0","type":"link"}