{"product_id":"dc-lamp-rabbit-pab-es8699","title":"DC-LAMP rabbit pAb - ES8699","description":"\u003cp\u003eDC-LAMP rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8699-50, ES8699-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Lysosome-associated membrane glycoprotein 3 (LAMP-3; Lysosomal-associated membrane protein 3; DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403; CD antigen CD208)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthetic peptide from human protein at AA range: 261-310\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 44kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 27074\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9UQV4\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell surface. Lysosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3 (PubMed:9768752). Detected on lysosomes in mature dendritic cells (PubMed:9768752).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202390286515,"sku":"ES8699-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202390319283,"sku":"ES8699-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_58d50326-ce3c-45a7-8f52-72abf5163bb7.png?v=1767128108","url":"https:\/\/afsbio.com\/products\/dc-lamp-rabbit-pab-es8699","provider":"AFSBio Inc.","version":"1.0","type":"link"}