{"product_id":"dcamkl3-polyclonal-antibody-bt-ap02516","title":"DCAMKL3 Polyclonal Antibody - BT-AP02516","description":"\u003cp\u003eDCAMKL3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02516-20, BT-AP02516-50, BT-AP02516-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine\/threonine (Ser\/Thr) protein kinases. DCAMKL3 (doublecortin-like and CAM kinase-like 3), also known as DCLK3 or DCDC3C, is a 648 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain. One of several members of the Ser\/Thr protein kinase family, DCAMKL3 functions to catalyze the ATP-dependent attachment of a phospho residue to target proteins, an event that may play a role in various cellular processes.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DCLK3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: DCAMKL3 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 73814\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9C098; Mouse: Q8BWQ5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DCLK3; DCAMKL3; DCDC3C; KIAA1765; Serine\/threonine-protein kinase DCLK3; Doublecortin domain-containing protein 3C; Doublecortin-like and CAM kinase-like 3; Doublecortin-like kinase 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 85443\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240257282227,"sku":"BT-AP02516-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240257314995,"sku":"BT-AP02516-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240257347763,"sku":"BT-AP02516-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8e1bdd40-33f3-4c15-a2e7-55d94ad0ea8b.png?v=1769405825","url":"https:\/\/afsbio.com\/products\/dcamkl3-polyclonal-antibody-bt-ap02516","provider":"AFSBio Inc.","version":"1.0","type":"link"}