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DDLAC Reagent - 250mg

DDLAC Reagent - 250mg

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$236.21 CAD
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DDLAC is a non-ionic detergent / surfactant with a lactobionamide head group and a dodecyl chain.

N-dodecylamine lactobionamide

Compound name: N-dodecylamine lactobionamide (DDLAC)

Catalogue number: DDLAC_250MG

Molec. Formula: C24H47NO11

CAS: nd

MW: 525.6 g/mol

pKa: na​

Percent Composition: C, 54.84; H, 9.01; N, 2.66; O, 33.48

 

Physical state: White powder

Purity (HPLC, 214nm): ≤95%

Retention time (RP18 HPLC)b: tR = 14.9 min

CMC: 0.25 mM

Exact mass​: 525.3149

Stability: Store in <-20°C freezer for up to one year

Solubility Structure: Soluble in water (1.25mM), methanol and DMSO

 


CALIXAR uses a unique & custom-built approach

CALIXAR’s DDLAC is produced into a powder form and is utilized in an aqueous solution or buffer. DDLAC can be mixed with biological materials (biological membranes).

Our clients are able to use DDLAC to aid in the production of lipid detergents, mixed micelles, and protein detergent micelles. DDLAC enables clients to extract, to solubilize and to stabilize native and functional membrane proteins of high medical relevance within a solution.

DDLAC is a fairly mild detergent used to solubilize and stabilize native membrane proteins that are non-ionic. Consequently, as it is not sensitive to ionic strength or pH variations, they are ideal to extract precise membrane proteins.

CALIXAR’s DDLAC is non-ionic and therefore not sensitive to ionic concentration or pH shifts.  DDLAC is well adapted to extract, to solubilize and to stabilize particular membrane proteins.

CALIXAR’s DDLAC (N-dodecylamine lactobionamide) extracts high-quality membrane proteins used for research, drug discovery and structural studies. Our DDLAC is specifically made for pharmaceutical and biotechnology companies, as well as academic teams (biochemists, structural biologists, pharmacologists, virologists) involved in the life science domains. 

 

  • Antibodies (including nanobodies, scaffold proteins, aptamers)
  • Small molecules
  • 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
  • Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
  • Antibody discovery (Immunization and display technologies)
  • Clinical stage

References

ACS PUBLICATIONS

Lactobionamide Surfactants with Hydrogenated, Perfluorinated or Hemifluorinated Tails

Lebaupain F. et al. 2006