{"product_id":"dedd-polyclonal-antibody-bt-ap15208","title":"DEDD Polyclonal Antibody - BT-AP15208","description":"\u003cp\u003eDEDD Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15208-20, BT-AP15208-50, BT-AP15208-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DEDD\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Death effector domain-containing protein\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O75618; Mouse: Q9Z1L3; Rat: Q9Z2K0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Death effector domain-containing protein;DEDPro1;Death effector domain-containing testicular molecule;FLDED-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9191\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239116136627,"sku":"BT-AP15208-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239116169395,"sku":"BT-AP15208-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239116202163,"sku":"BT-AP15208-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a26032c9-4c25-4e14-9ba3-d2d43fc4c316.png?v=1769389329","url":"https:\/\/afsbio.com\/products\/dedd-polyclonal-antibody-bt-ap15208","provider":"AFSBio Inc.","version":"1.0","type":"link"}