{"product_id":"defensinalpha3-polyclonal-antibody-bt-ap02562","title":"DefensinAlpha3 Polyclonal Antibody - BT-AP02562","description":"\u003cp\u003eDefensinAlpha3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02562-20, BT-AP02562-50, BT-AP02562-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Neutrophil defensin 3 encoded by DEFA3, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. DEFA3 differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DEFA3\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Defensin alpha3 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 10245\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P59666\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DEFA3; DEF3; Neutrophil defensin 3; Defensin; alpha 3; HNP-3; HP-3; HP3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1668\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240260231347,"sku":"BT-AP02562-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240260264115,"sku":"BT-AP02562-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240260296883,"sku":"BT-AP02562-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f2034062-a34f-4fc5-a205-7ef9aeb68d84.png?v=1769405868","url":"https:\/\/afsbio.com\/products\/defensinalpha3-polyclonal-antibody-bt-ap02562","provider":"AFSBio Inc.","version":"1.0","type":"link"}