{"product_id":"dgcr8-rabbit-polyclonal-antibody-bt-ap09158","title":"DGCR8 Rabbit Polyclonal Antibody - BT-AP09158","description":"\u003cp\u003eDGCR8 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09158-20, BT-AP09158-50, BT-AP09158-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein| Drosha. Alternate splicing results in multiple transcript variants.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DGCR8\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: DGCR8\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8WYQ5; Mouse: Q9EQM6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DGCR8; Microprocessor complex subunit DGCR8; DiGeorge syndrome critical region 8)\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 54487; Mouse: 94223\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238991945907,"sku":"BT-AP09158-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238991978675,"sku":"BT-AP09158-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238992011443,"sku":"BT-AP09158-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_685694da-e144-48ab-8908-71e9cbeda9df.png?v=1769387638","url":"https:\/\/afsbio.com\/products\/dgcr8-rabbit-polyclonal-antibody-bt-ap09158","provider":"AFSBio Inc.","version":"1.0","type":"link"}