{"product_id":"dgk-α-a340-polyclonal-antibody-bs1960","title":"DGK-α (A340) Polyclonal Antibody-BS1960","description":"\u003cp\u003eDGK-α (A340) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1960-50, BS1960-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P23743\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eBackground: Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol (DAG) to produce phosphatidic acid. DAG and phosphatidic acid are lipids that act as second messengers in signaling cascades. DGK-alpha influences cell activation and secretion of lethal exosomes, which in turn control cell death. DGK-beta is abundant in restricted brain regions such as the caudate putamen and olfactory tubercle. DGK-gamma encodes full-length and truncated transcripts that are present in a range of human tissues, with greatest expression observed in retina. DGK-delta is most abundant in skeletal muscle. DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol and is expressed predominantly in testis. DGK-zeta is most abundant in brain and muscle. DGK-eta is closely related to DGK-delta. DGK-theta is most abundant in the cerebellum and hippocampus.\u003c\/p\u003e \n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: DGK-α (A340) polyclonal antibody detects endogenous levels of DGK-α protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of DGK-α (A340) pAb at 1:2000 dilution\u003cbr\u003e\nLane 1: C6 whole cell lysate (40ug)\u003cbr\u003e\nLane 2: U-87MG whole cell lysate (40ug)\u003cbr\u003e\nLane 3: Myla2059 whole cell lysate (40ug)\u003cbr\u003e\nLane 4: HuT78 whole cell lysate (10ug), Immunohistochemistry (IHC) analyzes of DGK-α (A340) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.\u003c\/p\u003e \n\n\u003cp\u003eBioworld Molecular Weight: ~ 90 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Diacylglycerol kinase alpha; DAG kinase alpha; 80 kDa diacylglycerol kinase; Diglyceride kinase alpha; DGK-alpha; DGKA; DAGK; DAGK1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 310-360 of Human DGK-α.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42953203646643,"sku":"BS1960-50","price":254.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42953203679411,"sku":"BS1960-100","price":442.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_0caafdd8-358b-4f4f-8bdc-f17567cfd819.jpg?v=1705056691","url":"https:\/\/afsbio.com\/products\/dgk-%ce%b1-a340-polyclonal-antibody-bs1960","provider":"AFSBio Inc.","version":"1.0","type":"link"}