{"product_id":"dgka-mouse-monoclonal-antibody-mb67304","title":"DGKA Mouse Monoclonal Antibody - MB67304","description":"\u003cp\u003eDGKA Mouse Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 25μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB67304-25, MB67304-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Troponin proteins associate with tropomyosin and regμlate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adμlts. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: SSTNI, TNN1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fμll length human recombinant protein of human TNNI1 (NP_003272) produced in E.coli.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500, IHC 1:150\u003c\/p\u003e\n\n\u003cp\u003ePurification: Purified from mouse ascites fluids or tissue cμlture supernatant by affinity chromatography (protein A\/G)\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: DGKA mouse monoclonal antibody detects endogenous levels of DGKA protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 80 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P19237\u003c\/p\u003e\n\n\u003cp\u003eProduct: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"25μl","offer_id":45946137444531,"sku":"MB67304-25","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946137477299,"sku":"MB67304-100","price":642.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/dgka-mouse-monoclonal-antibody-mb67304","provider":"AFSBio Inc.","version":"1.0","type":"link"}