{"product_id":"dhb2-rabbit-polyclonal-antibody-es9653","title":"DHB2 Rabbit Polyclonal Antibody - ES9653","description":"\u003cp\u003eDHB2 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES9653-50, ES9653-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: catalytic activity:Estradiol-17-beta + NAD(P)(+) = estrone + NAD(P)H.,catalytic activity:Testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH.,function:Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.,similarity:Belongs to the short-chain dehydrogenases\/reductases (SDR) family.,\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse,\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from part region of human protein\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: DHB2\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: DHB2 Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Expressed in placenta,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 42kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis\u003c\/p\u003e\n\n\u003cp\u003eFunction: Catalytic Activity: Estradiol-17-beta + NAD(P)(+) = estrone + NAD(P)H\u003cbr\u003e\nCatalytic Activity: Testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH\u003cbr\u003e\nFunction: Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH\u003cbr\u003e\nSimilarity: Belongs to the short-chain dehydrogenases\/reductases (SDR) family\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Endoplasmic reticulum membrane, Single-pass type II membrane protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: HSD17B2 EDH17B2\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Microsomal 17-beta-hydroxys\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: P51658\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: Q62730\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46314150199475,"sku":"ES9653-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46314150232243,"sku":"ES9653-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/dhb2-rabbit-polyclonal-antibody-es9653","provider":"AFSBio Inc.","version":"1.0","type":"link"}