{"product_id":"dicer-polyclonal-antibody-bt-ap08495","title":"DICER Polyclonal Antibody - BT-AP08495","description":"\u003cp\u003eDICER Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08495-20, BT-AP08495-50, BT-AP08495-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DICER1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Endoribonuclease Dicer\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UPY3; Mouse: Q8R418\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Endoribonuclease Dicer;EC 3.1.26.-;Helicase with RNase motif;Helicase MOI\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 23405\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239119347891,"sku":"BT-AP08495-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239119380659,"sku":"BT-AP08495-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239119413427,"sku":"BT-AP08495-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ef6dab63-69da-484b-8f1c-0bfe63735b11.png?v=1769389366","url":"https:\/\/afsbio.com\/products\/dicer-polyclonal-antibody-bt-ap08495","provider":"AFSBio Inc.","version":"1.0","type":"link"}