{"product_id":"dimethyl-dnmt3a-k44-polyclonal-antibody-bs74110","title":"DiMethyl-DNMT3A-K44 Polyclonal Antibody-BS74110","description":"\u003cp\u003eDiMethyl-DNMT3A-K44 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers:BS74110-50, BS74110-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O88508\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF\/ICC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IF\/ICC,1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.\u003c\/p\u003e \n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003cbr\u003e\nSpecificity: Methylated\u003c\/p\u003e \n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunofluorescence analysis of U2OS cells using DiMethyl-DNMT3A-K44 antibody at dilution of 1:100. Blue: DAPI for nuclear staining., Immunofluorescence analysis of C6 cells using DiMethyl-DNMT3A-K44 antibody at dilution of 1:100. Blue: DAPI for nuclear staining., Immunofluorescence analysis of HeLa cells using DiMethyl-DNMT3A-K44 antibody at dilution of 1:100. Blue: DAPI for nuclear staining., Immunofluorescence analysis of NIH\/3T3 cells using DiMethyl-DNMT3A-K44 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Dnmt3a;MmuIIIA;DNMT3A2;M.HsaIIIA;TBRS\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic dimethylated peptide around K44 of mouse DNMT3A(NP_031898.1).\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Methylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42895049588915,"sku":"BS74110-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42895049621683,"sku":"BS74110-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e832e5a8-e393-46e5-bc8b-3ed5abafa570.jpg?v=1702573050","url":"https:\/\/afsbio.com\/products\/dimethyl-dnmt3a-k44-polyclonal-antibody-bs74110","provider":"AFSBio Inc.","version":"1.0","type":"link"}