{"product_id":"dimethyl-dnmt3a-k44-rabbit-pab-a16012","title":"DiMethyl-DNMT3A-K44 Rabbit pAb - A16012","description":"\u003cp\u003eDiMethyl-DNMT3A-K44 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A16012-20, A16012-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Loss of function of this gene causes developmental defects in multiple different organ systems. There is a pseudogene for this gene located on chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed.\u003c\/p\u003e\n\n\u003cp\u003eApplications: Methylated Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF\/ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 102kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 13435\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O88508\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: MmuIIIA; DiMethyl-DNMT3A-K44\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: IF\/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics \u0026amp; Nuclear Signaling, Epigenetic Modifications, Methylation.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Dnmt3a\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189427003571,"sku":"A16012-20","price":179.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189427036339,"sku":"A16012-100","price":515.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_774f4cf7-f7db-4082-b9e8-54598c67ac52.png?v=1766426960","url":"https:\/\/afsbio.com\/products\/dimethyl-dnmt3a-k44-rabbit-pab-a16012","provider":"AFSBio Inc.","version":"1.0","type":"link"}