{"product_id":"dlrb1-polyclonal-antibody-bt-ap08517","title":"DLRB1 Polyclonal Antibody - BT-AP08517","description":"\u003cp\u003eDLRB1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08517-20, BT-AP08517-50, BT-AP08517-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DYNLRB1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Dynein light chain roadblock-type 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9NP97; Mouse: P62627; Rat: P62628\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Dynein light chain roadblock-type 1;Bithoraxoid-like protein;BLP;Dynein light chain 2A, cytoplasmic;Dynein-associated protein Km23;Roadblock domain-containing protein 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 83658\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239120887987,"sku":"BT-AP08517-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239120920755,"sku":"BT-AP08517-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239120953523,"sku":"BT-AP08517-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e39163dc-9eb2-453b-b10c-0a72f1908e67.png?v=1769389393","url":"https:\/\/afsbio.com\/products\/dlrb1-polyclonal-antibody-bt-ap08517","provider":"AFSBio Inc.","version":"1.0","type":"link"}