{"product_id":"dlrb1-rabbit-polyclonal-antibody-es9617","title":"DLRB1 Rabbit Polyclonal Antibody - ES9617","description":"\u003cp\u003eDLRB1 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES9617-50, ES9617-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from part region of human protein AA range: 1-50\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: DLRB1\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: DLRB1 Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: High expression in heart, liver, brain and pancreas, moderate in placenta, skeletal muscle and kidney, low in lung, prostate, testis, small intestine and colon, Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 10kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Salmonella infection\u003c\/p\u003e\n\n\u003cp\u003eFunction: Alternative Products: Additional isoforms seem to exist,Function: May be involved in assembly and motor function of dynein, which plays a central role in cell division and intracellular transport\u003cbr\u003e\nMiscellaneous: Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients\u003cbr\u003e\nSimilarity: Belongs to the GAMAD family\u003cbr\u003e\nSubunit: Homodimer\u003cbr\u003e\nTissue Specificity: High expression in heart, liver, brain and pancreas, moderate in placenta, skeletal muscle and kidney, low in lung, prostate, testis, small intestine and colon\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Cytoplasm, cytoskeleton\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: DYNLRB1 BITH DNCL2A DNLC2A ROBLD1 HSPC162\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Dynein light chain roadblock-type 1 (Bithoraxoid-like protein) (BLP) (Dynein light chain 2A, cytoplasmic) (Dynein-associated protein Km23) (Roadblock domain-containing protein 1)\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: P62627\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: P62628\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46314144891059,"sku":"ES9617-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46314144923827,"sku":"ES9617-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/dlrb1-rabbit-polyclonal-antibody-es9617","provider":"AFSBio Inc.","version":"1.0","type":"link"}