{"product_id":"dmbt1-polyclonal-antibody-bt-ap08524","title":"DMBT1 Polyclonal Antibody - BT-AP08524","description":"\u003cp\u003eDMBT1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08524-20, BT-AP08524-50, BT-AP08524-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DMBT1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Deleted in malignant brain tumors 1 protein\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UGM3; Mouse: Q60997; Rat: Q8CIZ5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Deleted in malignant brain tumors 1 protein;Glycoprotein 340;Gp-340;Hensin;Salivary agglutinin;SAG;Surfactant pulmonary-associated D-binding protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1755\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239121182899,"sku":"BT-AP08524-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239121215667,"sku":"BT-AP08524-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239121248435,"sku":"BT-AP08524-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_52a18145-d31c-4eff-95c4-e3446c9848b3.png?v=1769389397","url":"https:\/\/afsbio.com\/products\/dmbt1-polyclonal-antibody-bt-ap08524","provider":"AFSBio Inc.","version":"1.0","type":"link"}