{"product_id":"dmgdh-polyclonal-antibody-bt-ap02645","title":"DMGDH Polyclonal Antibody - BT-AP02645","description":"\u003cp\u003eDMGDH Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02645-20, BT-AP02645-50, BT-AP02645-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: DMGDH encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme (dimethylglycine dehydrogenase) is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DMGDH\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: DMGDH Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 96807\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UI17; Mouse: Q9DBT9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DMGDH; Dimethylglycine dehydrogenase; mitochondrial; ME2GLYDH\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 29958\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240264261811,"sku":"BT-AP02645-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240264294579,"sku":"BT-AP02645-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240264327347,"sku":"BT-AP02645-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ba85f89f-5a16-4ec5-b0a3-e592b6ab7136.png?v=1769405921","url":"https:\/\/afsbio.com\/products\/dmgdh-polyclonal-antibody-bt-ap02645","provider":"AFSBio Inc.","version":"1.0","type":"link"}