{"product_id":"dmgdh-polyclonal-antibody-e-ab-17889","title":"DMGDH Polyclonal Antibody - E-AB-17889","description":"\u003cp\u003eDMGDH Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-17889-60, E-AB-17889-120, E-AB-17889-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: DMGDH\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Dimethylglycine dehydrogenase; Dimethylglycine dehydrogenase; mitochondrial; Dmgdh; M2GD; ME2GLYDH; mitochondrial\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Metabolism, Neuroscience, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9UI17\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 2.1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human DMGDH\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 97 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143867957427,"sku":"E-AB-17889-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143867990195,"sku":"E-AB-17889-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143868022963,"sku":"E-AB-17889-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2f55f1cd-029d-4374-8f62-e5b59df741b5.png?v=1710242753","url":"https:\/\/afsbio.com\/products\/dmgdh-polyclonal-antibody-e-ab-17889","provider":"AFSBio Inc.","version":"1.0","type":"link"}