{"product_id":"dna-ligase-i-polyclonal-antibody-bs90416","title":"DNA Ligase I Polyclonal Antibody-BS90416","description":"\u003cp\u003eDNA Ligase I Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90416-50, BS90416-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P18858(Human) 37227(Rat)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500\u003cbr\u003e\nIHC:1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: DNA Ligase I polyclonal antibody detects endogenous levels of DNA Ligase I protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Predicted band size 102 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of DNA Ligase I on different cell lysates using anti-DNA Ligase I antibody at 1\/500 dilution.\u003cbr\u003e\n Positive control:\u003cbr\u003e\n Lane 1: Daudi \u003cbr\u003e\n Lane 2: A431\u003cbr\u003e\n Lane 3: MCF-7, Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-DNA Ligase I antibody. Counter stained with hematoxylin.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: LIG1, DNA ligase 1, DNA ligase I, DNLI1, LIG 1, lig1, Ligase I DNA ATP dependent, MGC117397, MGC130025, Polydeoxyribonucleotide synthase [ATP] 1,\u003c\/p\u003e \n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42979806740659,"sku":"BS90416-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42979806773427,"sku":"BS90416-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_65a5b2d5-8db7-475b-ae24-2ce58b8d1336.jpg?v=1705753017","url":"https:\/\/afsbio.com\/products\/dna-ligase-i-polyclonal-antibody-bs90416","provider":"AFSBio Inc.","version":"1.0","type":"link"}