{"product_id":"dna-ligase-iii-rabbit-pab-es2182","title":"DNA Ligase III rabbit pAb - ES2182","description":"\u003cp\u003eDNA Ligase III rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES2182-50, ES2182-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: LIG3; DNA ligase 3; DNA ligase III; Polydeoxyribonucleotide synthase [ATP] 3\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from DNA Ligase III . at AA range: 110-190\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 100kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3980\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P49916\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: [Isoform 1]: Mitochondrion. Contains an N-terminal mitochondrial transit peptide.; [Isoform 2]: Mitochondrion. Contains an N-terminal mitochondrial transit peptide.; [Isoform 3]: Nucleus. Lacks the N-terminal mitochondrial transit peptide.; [Isoform 4]: Nucleus. Lacks the N-terminal mitochondrial transit peptide.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202060083379,"sku":"ES2182-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202060116147,"sku":"ES2182-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_70f9c484-ff11-46f7-bf30-c41a5cc17b96.png?v=1767120979","url":"https:\/\/afsbio.com\/products\/dna-ligase-iii-rabbit-pab-es2182","provider":"AFSBio Inc.","version":"1.0","type":"link"}