{"product_id":"dna-pol-β-acetyl-lys72-rabbit-polyclonal-antibody-ra24248","title":"DNA pol β (Acetyl Lys72) Rabbit Polyclonal Antibody - RA24248","description":"\u003cp\u003eDNA pol β (Acetyl Lys72) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA24248-50, RA24248-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: catalytic activity:Deoxynucleoside triphosphate + DNA (n) = diphosphate + DNA (n+1) .,cofactor:Binds 2 magnesium ions per subunit.,domain:Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.,function:Repair polymerase. Conducts \"gap-filling\" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.,PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.,similarity:Belongs to the DNA polymerase type-X family.,subunit:Monomer.,\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: DNA polymerase beta (EC 2.7.7.7;EC 4.2.99.-)\u003c\/p\u003e \n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 5423\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 38\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P06746\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121243611315,"sku":"RA24248-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121243644083,"sku":"RA24248-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_18871737-d213-4876-9079-e471521501a0.png?v=1773345638","url":"https:\/\/afsbio.com\/products\/dna-pol-%ce%b2-acetyl-lys72-rabbit-polyclonal-antibody-ra24248","provider":"AFSBio Inc.","version":"1.0","type":"link"}