{"product_id":"dna-pol-δ-3-polyclonal-antibody-bs5699","title":"DNA pol δ 3 Polyclonal Antibody-BS5699","description":"\u003cp\u003eDNA pol δ 3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS5699-50, BS5699-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: DNA polymerase delta subunit 3; DNA polymerase delta subunit p66; POLD3; KIAA0039; DNA pol δ3; DNA polδ3; DNApolδ3; DNA pol δ p66; DNA polδ p66\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q15054\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB ICC\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nICC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases, namely DNA pol α, β, δ and ε. DNA pol δ and DNA pol ε are multisubunit enzymes, with DNA pol δ consisting of two subunits which interact with the sliding DNA clamp protein PCNA. DNA pol δ 3, also known as POLD3 or p66, is a 466 amino acid nuclear protein that is required for the proper function of DNA pol δ.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: DNA pol δ 3 polyclonal antibody detects endogenous levels of DNA pol δ 3 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 51 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of DNA pol δ 3 pAb at 1:500 dilution\u003cbr\u003e\nLane 1: HuT78 whole cell lysate(40ug)\u003cbr\u003e\nLane 2: Myla2059 whole cell lysate(40ug)\u003cbr\u003e\nLane 3: SGC7901 whole cell lysate(40ug)\u003cbr\u003e\nLane 4: The Testis tissue lysate of Mouse(40ug)\u003cbr\u003e\nLane 5: PC12 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to the 421-466 of Human DNA pol δ 3.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42911812321459,"sku":"BS5699-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42911812354227,"sku":"BS5699-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_ca2d9e66-4b50-4da8-a28b-64c89e27ff72.jpg?v=1703179787","url":"https:\/\/afsbio.com\/products\/dna-pol-%ce%b4-3-polyclonal-antibody-bs5699","provider":"AFSBio Inc.","version":"1.0","type":"link"}