{"product_id":"dna-pol-epsilon-a-polyclonal-antibody-bt-ap02661","title":"DNA pol Epsilon A Polyclonal Antibody - BT-AP02661","description":"\u003cp\u003eDNA pol Epsilon A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02661-20, BT-AP02661-50, BT-AP02661-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: POLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: POLE\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: DNA pol epsilon A Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 261518\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q07864; Mouse: Q9WVF7\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: POLE; POLE1; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5426\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240265441459,"sku":"BT-AP02661-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240265474227,"sku":"BT-AP02661-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240265506995,"sku":"BT-AP02661-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7a152453-26fb-4253-8896-b4018f7995f2.png?v=1769405939","url":"https:\/\/afsbio.com\/products\/dna-pol-epsilon-a-polyclonal-antibody-bt-ap02661","provider":"AFSBio Inc.","version":"1.0","type":"link"}