{"product_id":"dnjc2-polyclonal-antibody-bt-ap08569","title":"DNJC2 Polyclonal Antibody - BT-AP08569","description":"\u003cp\u003eDNJC2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08569-20, BT-AP08569-50, BT-AP08569-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DNAJC2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: DnaJ homolog subfamily C member 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q99543; Mouse: P54103; Rat: Q7TQ20\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DnaJ homolog subfamily C member 2;M-phase phosphoprotein 11;Zuotin-related factor 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 27000\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239122198707,"sku":"BT-AP08569-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239122231475,"sku":"BT-AP08569-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239122264243,"sku":"BT-AP08569-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_fda0c9b8-0e93-4906-92bb-b0f7901de23a.png?v=1769389413","url":"https:\/\/afsbio.com\/products\/dnjc2-polyclonal-antibody-bt-ap08569","provider":"AFSBio Inc.","version":"1.0","type":"link"}