{"product_id":"dnm2-polyclonal-antibody-e-ab-65563","title":"DNM2 Polyclonal Antibody - E-AB-65563","description":"\u003cp\u003eDNM2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-65563-60, E-AB-65563-120, E-AB-65563-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: DNM2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: DNM2; CMT2M; CMTDI1; CMTDIB; DI-CMTB; DYN2; DYNII; LCCS5; dynamin-2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P50570\u003c\/p\u003e\n\n\u003cp\u003eBackground: Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human DNM2 (NP_004936.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 97kDa\/98kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 125kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146376347827,"sku":"E-AB-65563-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146376380595,"sku":"E-AB-65563-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146376413363,"sku":"E-AB-65563-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e6f6a360-64fd-40fc-bde7-8161de5e9c7c.png?v=1710294521","url":"https:\/\/afsbio.com\/products\/dnm2-polyclonal-antibody-e-ab-65563","provider":"AFSBio Inc.","version":"1.0","type":"link"}