{"product_id":"dock-180-k1692-polyclonal-antibody-bs3846","title":"DOCK 180 (K1692) Polyclonal Antibody-BS3846","description":"\u003cp\u003eDOCK 180 (K1692) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3846-50, BS3846-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: DOCK180; DOCK-180; dedicator of cytokinesis; 180 kDa; DOCK1; DOCK-1; dedicator of cytokinesis 1; ced5\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q14185\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: DOCK 180, a 180 kDa protein downstream of Crk, has been identified as a major Crk-associated protein. When DOCK 180 is recruited to the plasma membrane from a cytoplasmic reservoir, presumably by Crk, changes in cellular morphology and spindle formation occur, suggesting DOCK 180 to be a Crk effector molecule\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: DOCK 180 (K1692) polyclonal antibody detects endogenous levels of DOCK 180 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 215 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of DOCK1 pAb at 1:500 dilution\u003cbr\u003e\nLane 1: MCF-7 whole cell lysate(40ug)\u003cbr\u003e\nLane 2: H1792 whole cell lysate(40ug)\u003cbr\u003e\nLane 3: C6 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 1660-1719 of Human DOCK 180.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42911806783667,"sku":"BS3846-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42911806816435,"sku":"BS3846-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_54601ad1-3ddc-4520-9c3d-fe2554499d79.jpg?v=1703179636","url":"https:\/\/afsbio.com\/products\/dock-180-k1692-polyclonal-antibody-bs3846","provider":"AFSBio Inc.","version":"1.0","type":"link"}