{"product_id":"dock2-polyclonal-antibody-e-ab-67583","title":"DOCK2 Polyclonal Antibody - E-AB-67583","description":"\u003cp\u003eDOCK2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-67583-120, E-AB-67583-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: DOCK2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: DOCK2; IMD40\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q92608\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human DOCK2 (NP_004937.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 38kDa\/211kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 240kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"120μL","offer_id":43149055459507,"sku":"E-AB-67583-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43149055492275,"sku":"E-AB-67583-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_1bbbed95-a0e5-47c1-9c1f-3e914c839e79.png?v=1710339341","url":"https:\/\/afsbio.com\/products\/dock2-polyclonal-antibody-e-ab-67583","provider":"AFSBio Inc.","version":"1.0","type":"link"}