{"product_id":"dpog1-polyclonal-antibody-bt-ap15298","title":"DPOG1 Polyclonal Antibody - BT-AP15298","description":"\u003cp\u003eDPOG1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15298-20, BT-AP15298-50, BT-AP15298-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: POLG\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: DNA polymerase subunit gamma-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P54098; Mouse: P54099; Rat: Q9QYV8\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DNA polymerase subunit gamma-1;EC 2.7.7.7;Mitochondrial DNA polymerase catalytic subunit;PolG-alpha\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5428\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239123312819,"sku":"BT-AP15298-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239123345587,"sku":"BT-AP15298-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239123378355,"sku":"BT-AP15298-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_99cf6fcf-84b0-4b14-8590-a5d5ebf96b78.png?v=1769389434","url":"https:\/\/afsbio.com\/products\/dpog1-polyclonal-antibody-bt-ap15298","provider":"AFSBio Inc.","version":"1.0","type":"link"}