{"product_id":"dr6-phospho-ser562-rabbit-polyclonal-antibody-bt-ap02307","title":"DR6 (Phospho-Ser562) Rabbit Polyclonal Antibody - BT-AP02307","description":"\u003cp\u003eDR6 (Phospho-Ser562) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02307-20, BT-AP02307-50, BT-AP02307-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1)| and induces cell apoptosis. Through its death domain| the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein| which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation| and may be involved in inflammation and immune regulation.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TNFRSF21\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: DR6\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O75509; Mouse: Q9EPU5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DR6;Ser562; Tumor necrosis factor receptor superfamily member 21; Death receptor 6; CD antigen CD358\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 27242; Mouse: 94185\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238992634035,"sku":"BT-AP02307-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238992666803,"sku":"BT-AP02307-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238992699571,"sku":"BT-AP02307-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_956eb2d6-2f1f-4450-b3fb-c259315af7ba.png?v=1769387649","url":"https:\/\/afsbio.com\/products\/dr6-phospho-ser562-rabbit-polyclonal-antibody-bt-ap02307","provider":"AFSBio Inc.","version":"1.0","type":"link"}