{"product_id":"dsc2-polyclonal-antibody-bt-ap08627","title":"DSC2 Polyclonal Antibody - BT-AP08627","description":"\u003cp\u003eDSC2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08627-20, BT-AP08627-50, BT-AP08627-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DSC2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Desmocollin-2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q02487; Mouse: P55292\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Desmocollin-2;Cadherin family member 2;Desmocollin-3;Desmosomal glycoprotein II;Desmosomal glycoprotein III\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1824\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239124197555,"sku":"BT-AP08627-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239124230323,"sku":"BT-AP08627-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239124263091,"sku":"BT-AP08627-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_dc274e79-19e1-4877-aed4-d9f2bea38542.png?v=1769389448","url":"https:\/\/afsbio.com\/products\/dsc2-polyclonal-antibody-bt-ap08627","provider":"AFSBio Inc.","version":"1.0","type":"link"}