{"product_id":"dsg1-polyclonal-antibody-e-ab-68430","title":"DSG1 Polyclonal Antibody - E-AB-68430","description":"\u003cp\u003eDSG1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-68430-60, E-AB-68430-120, E-AB-68430-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: DSG1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: DSG1; CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q02413\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human DSG1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IF 1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 42kDa\/113kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 150kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146500178099,"sku":"E-AB-68430-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146500210867,"sku":"E-AB-68430-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146500243635,"sku":"E-AB-68430-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_50811fb7-91a4-4e3f-8a28-cd67007e5727.png?v=1710296486","url":"https:\/\/afsbio.com\/products\/dsg1-polyclonal-antibody-e-ab-68430","provider":"AFSBio Inc.","version":"1.0","type":"link"}