{"product_id":"dsg3-monoclonal-antibody-bt-mca4276","title":"DSG3 Monoclonal Antibody - BT-MCA4276","description":"\u003cp\u003eDSG3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4276-50, BT-MCA4276-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DSG3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 6G2E2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: DSG3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human DSG3 (AA: 55-159) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 107.5kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P32926\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PVA, CDHF6\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1830\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238566518963,"sku":"BT-MCA4276-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238566551731,"sku":"BT-MCA4276-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c09866e7-364b-49f6-ba17-fa5140f5ca5f.png?v=1769382641","url":"https:\/\/afsbio.com\/products\/dsg3-monoclonal-antibody-bt-mca4276","provider":"AFSBio Inc.","version":"1.0","type":"link"}