{"product_id":"dusp19-polyclonal-antibody-ra24353","title":"DUSP19 Polyclonal Antibody - RA24353","description":"\u003cp\u003eDUSP19 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA24353-50, RA24353-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: dual specificity phosphatase 19 (DUSP19) Homo sapiens Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine\/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]) .[supplied by OMIM, Dec 2009],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: DUSP19; DUSP17; LMWDSP3; SKRP1; Dual specificity protein phosphatase 19; Dual specificity phosphatase TS-DSP1; Low molecular weight dual specificity phosphatase 3; LMW-DSP3; Protein phosphatase SKRP1; Stress-activated protein kinase pathway\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IF\/ICC; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Monkey\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 142679\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 28\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q8WTR2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121247740083,"sku":"RA24353-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121247772851,"sku":"RA24353-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_90953b1c-13ca-45f7-bf38-b218e1d6fa32.png?v=1773345688","url":"https:\/\/afsbio.com\/products\/dusp19-polyclonal-antibody-ra24353","provider":"AFSBio Inc.","version":"1.0","type":"link"}