{"product_id":"dusp27-polyclonal-antibody-e-ab-17896","title":"DUSP27 Polyclonal Antibody - E-AB-17896","description":"\u003cp\u003eDUSP27 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-17896-60, E-AB-17896-120, E-AB-17896-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: DUSP27\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: C130085G02Rik; DUS27; DUSP27; Gm209; Inactive dual specificity phosphatase 27; RGD1560598\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q5VZP5\u003c\/p\u003e\n\n\u003cp\u003eBackground: Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and\/or cellular stresses, thereby negatively regulating MAP kinase superfamily members, including MAPK\/ERK, SAPK\/JNK and p38. DUSP27 (dual specificity phosphatase 27), also known as FMDSP or DUPD1 (dual specificity phosphatase and pro isomerase domain containing 1), is a 220 amino acid cytoplasmic protein that belongs to the protein-tyrosine phosphatase family. Expressed in skeletal muscle, liver and adipose tissue, DUSP27 may play a role in energy metabolism. The gene encoding DUSP27 is referred to as DUPD1 and maps to human chromosome 10, which houses over 1, 200 genes and comprises nearly 4.5% of the human genome.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.92 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human DUSP27\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:300, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130662224051,"sku":"E-AB-17896-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130662256819,"sku":"E-AB-17896-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130662289587,"sku":"E-AB-17896-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_3cebf604-2160-43e1-b11f-def5388a76d8.png?v=1709810989","url":"https:\/\/afsbio.com\/products\/dusp27-polyclonal-antibody-e-ab-17896","provider":"AFSBio Inc.","version":"1.0","type":"link"}