{"product_id":"dvl1-polyclonal-antibody-bt-ap08649","title":"DVL1 Polyclonal Antibody - BT-AP08649","description":"\u003cp\u003eDVL1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08649-20, BT-AP08649-50, BT-AP08649-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DVL1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Segment polarity protein dishevelled homolog DVL-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O14640; Mouse: P51141; Rat: Q9WVB9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Segment polarity protein dishevelled homolog DVL-1;Dishevelled-1;DSH homolog 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1855\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239125409971,"sku":"BT-AP08649-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239125442739,"sku":"BT-AP08649-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239125475507,"sku":"BT-AP08649-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e459fec8-eb37-4a4d-9d0a-a7d91e43f766.png?v=1769389467","url":"https:\/\/afsbio.com\/products\/dvl1-polyclonal-antibody-bt-ap08649","provider":"AFSBio Inc.","version":"1.0","type":"link"}