{"product_id":"dylt1-polyclonal-antibody-bt-ap15343","title":"DYLT1 Polyclonal Antibody - BT-AP15343","description":"\u003cp\u003eDYLT1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15343-20, BT-AP15343-50, BT-AP15343-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Microbiology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DYNLT1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Dynein light chain Tctex-type 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P63172; Mouse: P51807; Rat: Q9Z336\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Dynein light chain Tctex-type 1;Protein CW-1;T-complex testis-specific protein 1 homolog\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6993\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239125606579,"sku":"BT-AP15343-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239125639347,"sku":"BT-AP15343-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239125672115,"sku":"BT-AP15343-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8d7e1e1a-c2a3-4f21-a48f-ba86e6a2585c.png?v=1769389471","url":"https:\/\/afsbio.com\/products\/dylt1-polyclonal-antibody-bt-ap15343","provider":"AFSBio Inc.","version":"1.0","type":"link"}