{"product_id":"dyn3-rabbit-polyclonal-antibody-es11026","title":"DYN3 Rabbit Polyclonal Antibody - ES11026","description":"\u003cp\u003eDYN3 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES11026-50, ES11026-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: approximately 7-10 business days, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: dynamin 3(DNM3) Homo sapiens This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],\u003c\/p\u003e \n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from part region of human protein\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: DYN3,\u003c\/p\u003e \n\n\u003cp\u003eSpecificity: DYN3 Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e \n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Brain, Kidney,\u003c\/p\u003e \n\n\u003cp\u003eObserved Band (KD): 95kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Phospholipase D signaling pathway, Endocytosis, Synaptic vesicle cycle, Endocrine and other factor-regulated calcium reabsorption, Bacterial invasion of epithelial cells\u003c\/p\u003e\n\n\u003cp\u003eFunction: Catalytic Activity: GTP + H(2)O = GDP + phosphate. Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis. Similarity: Belongs to the dynamin family. Similarity: Contains 1 GED domain. Similarity: Contains 1 PH domain. Subcellular Location: Microtubule-associated.\u003c\/p\u003e \n\n\u003cp\u003eSubcellular Location: Cytoplasm Cytoplasm, cytoskeleton Microtubule-associated.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: DNM3, KIAA0820\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Dynamin-3, EC 3.6.5.5, Dynamin, testicular, T-dynamin\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 26052\u003c\/p\u003e\n\n\u003cp\u003eHuman SwissProt Number: Q9UQ16\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q8BZ98\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: Q08877\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":45825499529395,"sku":"ES11026-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45825499562163,"sku":"ES11026-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk-biotechnology-logo-product.jpg?v=1786476023","url":"https:\/\/afsbio.com\/products\/dyn3-rabbit-polyclonal-antibody-es11026","provider":"AFSBio Inc.","version":"1.0","type":"link"}