{"product_id":"dynamin-i-phospho-ser774-rabbit-pab-es5010","title":"Dynamin I (phospho Ser774) rabbit pAb - ES5010","description":"\u003cp\u003eDynamin I (phospho Ser774) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES5010-50, ES5010-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: dynamin 1 (DNM1) Homo sapiens This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: DNM1; DNM; Dynamin-1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human Dynamin-1 around the phosphorylation site of Ser774. AA range:740-789\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 97kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 1759\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q05193\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Cytoplasm, cytoskeleton. Microtubule-associated.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202225823923,"sku":"ES5010-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202225856691,"sku":"ES5010-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_10721986-8022-43bb-a479-9d14efebeba1.png?v=1767124610","url":"https:\/\/afsbio.com\/products\/dynamin-i-phospho-ser774-rabbit-pab-es5010","provider":"AFSBio Inc.","version":"1.0","type":"link"}