{"product_id":"dynamin-i-polyclonal-antibody-bt-ap02765","title":"Dynamin I Polyclonal Antibody - BT-AP02765","description":"\u003cp\u003eDynamin I Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02765-20, BT-AP02765-50, BT-AP02765-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: DNM1 encodes a member of the dynamin subfamily of GTP-binding proteins. Dynamin-1 possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DNM1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Dynamin I Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 97407\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q05193; Mouse: P39053; Rat: P21575\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DNM1; DNM; Dynamin-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1759; Mouse: 13429; Rat: 140694\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240271274163,"sku":"BT-AP02765-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240271306931,"sku":"BT-AP02765-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240271339699,"sku":"BT-AP02765-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d6b00a45-1f33-45b5-b5ea-e7ec97596b0a.png?v=1769406031","url":"https:\/\/afsbio.com\/products\/dynamin-i-polyclonal-antibody-bt-ap02765","provider":"AFSBio Inc.","version":"1.0","type":"link"}