{"product_id":"dyrk2-polyclonal-antibody-bt-ap08669","title":"DYRK2 Polyclonal Antibody - BT-AP08669","description":"\u003cp\u003eDYRK2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08669-20, BT-AP08669-50, BT-AP08669-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground:  DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and\/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5andapos; terminal insert.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DYRK2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Dual specificity tyrosine-phosphorylation-regulated kinase 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q92630; Mouse: Q5U4C9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Dual specificity tyrosine-phosphorylation-regulated kinase 2;EC 2.7.12.1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8445\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239126130867,"sku":"BT-AP08669-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239126163635,"sku":"BT-AP08669-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239126196403,"sku":"BT-AP08669-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_13eddd93-54e0-44b9-a3f6-d76fac42635c.png?v=1769389478","url":"https:\/\/afsbio.com\/products\/dyrk2-polyclonal-antibody-bt-ap08669","provider":"AFSBio Inc.","version":"1.0","type":"link"}