{"product_id":"ear2-polyclonal-antibody-bt-ap02803","title":"EAR2 Polyclonal Antibody - BT-AP02803","description":"\u003cp\u003eEAR2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02803-20, BT-AP02803-50, BT-AP02803-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NR2F6, also known as Nuclear receptor subfamily 2 group F member 6, is a nuclear protein belonging to the nuclear hormone receptor family and NR2 subfamily with a nuclear receptor DNA-binding domain. NR2F6 is a nuclear receptor involved in action regulation of the transcription of the GNRH1 gene. It binds to the TGACCT repeat motif enhancing the renin gene and thus acting as a negative modulator of renin gene transcription. NR2F6 is required early in the development of the locus ceruleus (LC), thus in some way contributing to the regulation of the forebrain clock, at least in part, through targeted release of noradrenalin into the cortical area.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NR2F6\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: EAR2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 42979\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P10588; Mouse: P43136; Rat: O09017\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NR2F6; EAR2; ERBAL2; Nuclear receptor subfamily 2 group F member 6; V-erbA-related protein 2; EAR-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2063; Mouse: 13864; Rat: 245980\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240274321587,"sku":"BT-AP02803-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240274354355,"sku":"BT-AP02803-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240274387123,"sku":"BT-AP02803-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3a9a8b6c-07a4-4d69-8271-c6e2010e6709.png?v=1769406070","url":"https:\/\/afsbio.com\/products\/ear2-polyclonal-antibody-bt-ap02803","provider":"AFSBio Inc.","version":"1.0","type":"link"}